First appearance: the Brain that Wouldn't Die (1962)
I'm sure you've heard the story a million times before. A surgeon and his wife having a car accident. Surgeon takes wife's severed head and reanimates it in a pan in his private laboratory. Surgeon goes to strip clubs looking for a fancy new body for decapitated wife. Wife becomes psychically linked to weird conehead with a saggy butt created by surgeon husband. Wife becomes seriously depressed.